TGFB1 and lymphedema: Consistent with our findings, a decrease in the lymphatic vessel network and the possible occurrence of a Ly-EndMT process have been reported in age-related diseases [34,43,44], in experimental lymphedema [30], and in vitro in lymphatic ECs infected by Kaposi’s sarcoma herpesvirus or stimulated with TGFβ [30,32,45,46,47,48,49,50].