Then, using a myeloid cell-specific DNMT3B deficient mice, they demonstrated in the bleomycin-induced pulmonary fibrosis model that the lack of DNMT3B increased the recruitment of fibrotic AMs (SiglecFlowCD11bhi) as compared to classic alveolar macrophage population (SiglecFhiCD11blow). Here, DNMT3B is linked to pulmonary fibrosis.