For example, MSCs have been reported to promote tumorigenesis by secreting interleukin-8 (IL-8), IL-10, and indoleamine 2,3-dioxygenase (IDO) to suppress the immune system and by secreting vascular endothelial cell growth factor (VEGF), transforming growth factor-beta (TGF-β), and IL-6 to stimulate tumor vascularization [11]. This evidence concerns the gene TGFB1 and neoplasm.