ACE2 and Multiple Organ Failure: The pathophysiological mechanisms of cell invasion by a viral etiology include the presence of angiotensin-converting enzyme 2 (ACE2) in the inner and middle ear [6], disproportionate proinflammatory cytokines, wherein inflammation derived from NETosis plays an important role in the development of cytokine storm, sepsis, and multiple organ failure, in which surrounding tissue damage and coagulopathy could explain possible effects on the middle and inner ear [7].