Based on the ovarian cancer transcriptomic data in the TCGA‐OV dataset, we found that necroptosis‐related genes were significantly downregulated in patients with ovarian cancer aged ≥60 years (Figure 1A) and that 27.52% (71/258) of patients harbored genetic mutations, including JAK3, NLRP3, DNM1L, RNF31, PARP4, PLA2G4C, PYGL, and so on (Figure 1B). The gene discussed is PLA2G4C; the disease is ovarian cancer.