TFRC and neoplasm: One mechanism is related to the recruitment and education of different suppressor cells to build an immunosuppressive tumor microenvironment (TME), consisting of myeloid‐derived suppressor cells (MDSCs), neutrophils, tumor‐associated macrophages (TAMs), regulatory T cells (Tregs), and CD71+ erythroid cells (CECs) [2, 3, 4, 5].