However, contrary to our findings, Ding et al.15, found no evidence that a specific class of antihypertensive drugs was more effective than others in reducing the risk of dementia in their meta-analysis performed with six prospective studies, which analyzed the risk of developing dementia in hypertensive patients treated with one of five classes of antihypertensive drugs: angiotensin-converting enzyme inhibitors (ACEIs), angiotensin II receptor antagonists (ARBs), beta blockers, calcium channel blockers (including long- and short-acting preparations), and diuretics. The gene discussed is ACE; the disease is dementia.