MM is characterized by extensive osteolytic destruction, abnormal rise in monoclonal plasma cell ratio, osteolytic lesions, pathological fractures, anemia, hypercalcemia, nervous system damage, etc.9 In addition, monoclonal M protein increases in the patients, which inhibits the synthesis of polyclonal immunoglobulin and increases the risk of infections. The gene discussed is MYOM2; the disease is anemia (phenotype).