MM is characterized by extensive osteolytic destruction, abnormal rise in monoclonal plasma cell ratio, osteolytic lesions, pathological fractures, anemia, hypercalcemia, nervous system damage, etc.9 In addition, monoclonal M protein increases in the patients, which inhibits the synthesis of polyclonal immunoglobulin and increases the risk of infections. This evidence concerns the gene MYOM2 and hypercalcemia disease.