Further, B-cell lymphoma-2 (Bcl-2), ERK1/2, laminin A/C, and CK19 expressions have been found to be downregulated in FMN-treated NPC CNE2 cells, whereas intracellular Bax expression is elevated, indicating an inhibition of cell proliferation (Ying et al., 2019). The gene discussed is MAPK3; the disease is nasopharyngeal carcinoma.