Besides, we compared the expression of DRGGs between HCC tissues and normal samples and found that most genes, such as AGRN, B3GNT3 and FLNA, were highly expressed in tumor tissues (Figure 2E), resulting in a worse patient prognosis (Figures S1A–P, Figures S2A–P, Figures S3A–E). The gene discussed is AGRN; the disease is hepatocellular carcinoma.