The presence of vWF and platelets in areas of positive H3Cit staining in DVT was observed by assessing venous thromboembolism in surgical or autopsy specimens, demonstrating not only that histone citrullination occurs in DVT, but also that NETs, vWF, and platelets influence the formation and stability of DVT (83). The gene discussed is VWF; the disease is deep vein thrombosis.