MSH6 and mismatch repair cancer syndrome 1: Four of 6 cases with > 5 SNV + Indel/Mb and germline variations in MLH1, MSH2, MSH6, PMS2, POLE or POLD1 belonged to Myeloid Predominant, suggesting higher levels of immune infiltration in patients with biallelic Mismatch Repair Deficiency (bMMRD) syndrome.