Various tools are available for detecting telomere length and ALT status and mutational analysis including Telomere Shortest Length Assay (TESLA) as a technique that detects telomeres from all chromosome ends from < 1 kb to 18 kb using small amounts of DNA [190]; TERRA (the telomeric repeat-containing RNA) monitoring for the detection of ALT cancers [191], other reliable ALT biomarkers, such as C-circle and APBs [58] and next generation sequencing methods. This evidence concerns the gene GPT and cancer.