CD8A and esophageal squamous cell carcinoma: We assessed the correlation between ESRRG expression in the TCGA-ESCC dataset and immune scores using the MCPcounter software package in R. As illustrated in Fig. 7A, ESRRG was significantly correlated with T cells (R = 0.23, P < 0.05), CD8 + T cells (R = 0.36, P < 0.01), and NK cells (R = 0.28, P < 0.05).