The effects on cell viability (Fig. 6G), LDH release (Fig. 6H), cell membrane blebbing (Fig. 6I, Additional file 1: Fig. S3), and GSDME/caspase-3 cleavage (Fig. 6J, K) were enhanced after pretreatment with decitabine compared to treatment with Ven alone in both AML cell lines and patient-derived primary AML cells. The gene discussed is GSDME; the disease is acute myeloid leukemia.