GSDMD and bronchopulmonary dysplasia: A previous study from our laboratory demonstrated that hyperoxia-exposed GSDMD-KO animals had significantly less alveolar macrophage and neutrophil infiltration, an improvement in alveolarization and gas exchange surface area, improved vascularization and less vascular remodeling/muscularization compared to the WT mice indicating improvements in the hyperoxia-induced lung injury, and deranged alveolar and vascular development that are seen in BPD [21].