KDM6A and colorectal carcinoma: As indicated in Fig. 4F and G, organoid #Pv24 was the most sensitive organoid to GSK126 treatment with the lowest UTX expression, while organoid #Pv11 was the most resistant organoid to GSK126 treatment with the highest UTX expression, indicating an intrinsic reverse correlation between UTX expression and sensitivity to EZH2 inhibitor in human CRC.