INS and diabetes mellitus: Even for the diabetic patients, the levels of platelet reactivity and prevalence of HPR phenotypes varied depending on the need for insulin (Table 2); DM patients on insulin (N = 270, 6.7% of DM patients) showed the highest levels of platelet reactivity compared with other groups (DM on insulin vs. DM without insulin vs. non-DM: 44.0% vs. 37.7% vs. 32.0%, P < 0.001) Furthermore, we divided enrolled patients into the three groups according to on-admission HbA1c level (available data: n = 4,095); HbA1c < 6.5% (n = 2,541, 62.1%), 6.5–8.5% (n = 1,192, 29.1%) and > 8.5% (n = 362, 8.8%).