Finally, the AUC values of LGI, CRP, WBC, NLR, and PLT for predicting poor outcomes on day 90 were 0.682, 0.6533, 0.6258, 0.6712, and 0.52, respectively, indicating that the LGI score is more superior to other single indicators in predicting outcomes of ischemic stroke patients (Supplementary Figure 2). The gene discussed is CRP; the disease is ischemic stroke.