It is also notable that we documented 42 patients heterozygous for a single OTOF variant and with phenotypes compatible with otoferlin-related SNHL (Rodríguez-Ballesteros et al. 2003; Varga et al. 2003, 2006; Romanos et al. 2009; Chiu et al. 2010; Wang et al. 2010, 2011; Matsunaga et al. 2012; Iwasa et al. 2013), in addition to 14 heterozygous patients with late-onset, unilateral hearing loss that the authors suspected may have been related to otoferlin deficiency (Gao et al. 2021). Here, OTOF is linked to sensorineural hearing loss disorder.