GAPDH and infection: Indeed, simulated concentrations of the glycolytic metabolites G6-P (Fig. 3A) and 1,3BPG (Fig. 3B), generated by HK and GAPDH reactions, respectively, plus rate of production of lactate (Fig. 3C) and ATP production from glycolytic PGK (Fig. 3D) are highly upregulated upon infection and return to basal levels during the recovery phase.