As an approach to counteract atherosclerosis, upregulation of the long noncoding RNA (lncRNA) SNHG7-003, which is downregulated in response to ox-LDL treatment of VSMCs, sequesters miR-1306-5p from SIRT7 transcripts, thus preventing its downregulation (126). The gene discussed is SIRT7; the disease is atherosclerosis.