SYP and Wilson disease: However, most of these protein changes recovered to controlvalues after 14 days of the WD phase except Syp, which decreased significantly(P < 0.05) in METH-WD compared to the control.Furthermore, melatonin treatment causes a change in the expressionof proteins that are involved with GO terms concerning mitochondrialorganization, synaptic formation, or OXPHOS pathway when comparedto control and METH-WD mice with saline injection.