ENO2 and lung carcinoma: Subsequent multivariate Cox regression analysis further confirmed that PE was an independent prognostic factor (adjusted HR = 2.26, 95% CI 1.25–4.10, p < 0.001), after adjusting for age, sex, pathological type of lung cancer, NSE, WBC count, chemotherapy, antiangiogenesis therapy, immunotherapy, and ECOG PS score, which is consistent with the previous analysis.