The relevant cause of anaplastic astrocytoma is still unknown, but genetic and immunological deformities, stress, dietary habits, environmental factors like exposure to UV light, chemicals, ionizing radiations, a genetic disorder, for instance, NF1, tuberous sclerosis, and Li‐Fraumeni syndrome, hereditary predeposition may play a pivotal role in causing anaplastic astrocytoma according to the researcher's prediction. The gene discussed is NF1; the disease is anaplastic astrocytoma.