In the univariate analysis, factors that were identified to be significant predictors of the risk of HCC in NASH cirrhosis were older age (> 69 years), male sex, overweight/obesity, T2DM, hypertension, FIB-4 >3.25, albumin, INR, total bilirubin, and platelet count (Table 2). This evidence concerns the gene ALB and hepatocellular carcinoma.