In multivariable analyses, with adjustment for factors of interest based on univariate analysis, factors that maintained a significant association with HCC in NASH cirrhosis included (a) male sex, BMI 25-29.9 kg/m2, hypertension, and FIB-4 >3.25 in model 1.; (b) age >69 years, male sex, BMI 25-29.9 kg/m2, BMI 30-34.9 kg/m2, BMI 35-39.9 kg/m2, hypertension, and albumin in model 2; (c) male sex, BMI 25-29.9 kg/m2, BMI 30-34.9 kg/m2, BMI 35-39.9 kg/m2, hypertension, and albumin in model 3 (Table 2). The gene discussed is ALB; the disease is Hypertension.