The clinical characteristics of SARS CoV-2 can mimic the flare-up of rheumatic diseases, such as high-grade fever, arthralgia, myalgia, and fatigability, in addition to lymphopenia, a high erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and creatine kinase (CK). The gene discussed is CRP; the disease is lymphopenia.