Markers that are relevant for stress response and danger signaling, such as the alarmins S100A7, S100A8, and S100A9, the antimicrobial peptide lactotransferrin (LTF), and the interferon inducible protein (IFI27) were upregulated in KCs from AD patient skin treated with either Der p 2 rec or Der p 2 pep. This evidence concerns the gene S100A7 and Alzheimer disease.