Markers that are relevant for stress response and danger signaling, such as the alarmins S100A7, S100A8, and S100A9, the antimicrobial peptide lactotransferrin (LTF), and the interferon inducible protein (IFI27) were upregulated in KCs from AD patient skin treated with either Der p 2 rec or Der p 2 pep. Here, IFI27 is linked to Alzheimer disease.