The frequency of mBAFF positive B cells was higher in SLE patients compared with HS in the CXCR5+ CD11c- B cell subsets: DN1 (2.98% vs 2.04%, p = 0.0386), rNAV (3.12% vs 1.71%, p = 0.0009), CXCR5+ CD11c- SWM (2.87% vs 1.23%, p = 0.0005) and CXCR5+ CD11c- USM (4.16% vs 1.90%, p = < 0.0001) (Figures 3E–H). The gene discussed is CXCR5; the disease is systemic lupus erythematosus.