Whereas the DN and SWM B cells had lower expression of BR3 in SLE patients compared to HS (DN: 85.6% vs 94.4%, p = 0.0077 and SWM: 91.8% vs 95.8%, p = 0.0142 respectively) (Figures 3A, C). The gene discussed is TNFRSF13C; the disease is systemic lupus erythematosus.