In BC cells, interleukin IL-19 operates in an autocrine manner and stimulates the migration and proliferation, metastasis by up-regulating TGF-β, fibronectin, CXCR4, IL-6, IL-1β, MMP-9, and MMP-2 (Chen et al., 2013). The gene discussed is TGFB1; the disease is breast cancer.