While some cytokines like IL-11, IL-1, TGFβ, and IL-6 induce breast cancer proliferation and invasion, on the other hand, some cytokines like interferons (IFNs), IL-18, and IL12 inhibit breast cancer (BC) growth and proliferation (Esquivel-Velázquez et al., 2015). This evidence concerns the gene IL18 and breast carcinoma.