TNF and cervical squamous intraepithelial neoplasia: The network model shows the characteristics of cooperative regulation of multi-components, multi-targets, and multi-pathways in the treatment of A. manihot L. We found that the PI3K/AKT signaling pathway, FoxO signaling pathway, VEGF signaling pathway, HIF-1 signaling pathway, and TNF signaling pathway are important signaling pathways in the treatment of CIN.