No differences were observed in the subgroup with a tumor PD-L1 expression of 0% (median OS for G12C at 10.0 mo [95% CI: 6.6–13.3] versus median OS for non-G12C at 8.8 mo [95% CI: 6.8–9.8]; p = 0.80; Supplementary Fig. A.1B) and in the subgroup with PD-L1 at 1% to 49% (median OS for G12C at 16.0 mo [95% CI: 13.1–21.3] versus median OS for non-G12C at 12.2 mo [95% CI: 10.0–19.4], p = 0.43; Supplementary Fig. A.1C). The gene discussed is CD274; the disease is neoplasm.