BCHE and Alzheimer disease: Based on the cholinergic hypothesis in the fundamentals of developing neuropsychiatric symptoms of AD, cholinesterase inhibitors can not only improve cognitive function (Hampel et al., 2018) but also reverse and lessen altered brain oscillations in AD patients (Brassen and Adler, 2003; Rodriguez et al., 2004; Babiloni et al., 2006a; Gianotti et al., 2008).