PTP4A3 and osteosarcoma: Among 31 samples with complete clinical data available, PRL3 was more frequently expressed in embryonal tumors (neuroblastoma and Wilms tumor) compared with sarcomas (osteosarcoma, rhabdomyosarcoma, NRSTSs, and renal sarcomas) as well as in patients with regional and distant metastases compared with localized disease (Figure 3B).