Age (p=0.002), duration of diabetes (p=0.005), body mass (p=0.03), HDL among men (p=0.001), SGOT (p=0.03), insulin (p<0.001), HOMA-IR (p<0.001), and QUICKI (p<0.001) were significantly different between dietary GI tertiles. This evidence concerns the gene INS and diabetes mellitus.