And among all 10 patients with malignant diagnosis, there were 9 patients with positive CNV results (Figure 1B), including 5 cases lymphoma, 1 nasopharyngeal carcinoma, 1 gastric carcinoma, 1 liver cancer, and 1 case of polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes (POEMS) syndrome. Here, MYOM2 is linked to gastric carcinoma.