It was worth mentioning that, in the TC, patients with S15H (n = 32) had higher infiltration of CD8+ T cells than those with S15L (n = 157) only in the stroma area (P = 0.015), and had higher infiltration of TAMs than those with S15L in the total (P < 0.0001), tumor (P < 0.0001), or stroma area (P < 0.001) (Fig. 3F). Here, CD8A is linked to neoplasm.