Notably, these two agents exhibited reasonable growth inhibitory effects against MET-positive tumor cells, including AsPC-1 cells with MET overexpression (IC50: 8c = 15.3, 8h = 9.7μM) and MET gene amplified cancer cells EBC-1 (IC50: 8c = 19.0 and 8h = 6.1 μM) and MKN-45 (IC50: 8c = 22.0, 8h = 12.0 μM)30–34. Here, MET is linked to neoplasm.