Notably, among all known ligand-receptor pairs, DMD collagen signaling was mainly dominated by collagen I, IV and VI and its receptor Itga1/Itga2 + Itgb1. FAPs were also the most prominent source of laminin either in control and DMD samples, although adipocytes became an important source as well in DMD (Fig. 8). The gene discussed is ITGA1; the disease is Duchenne muscular dystrophy.