To investigate whether Cebpb was sufficient to drive EG within infection-naïve larvae, we generated a transgenic line overexpressing cebpb within HSPCs using the mouse Runx1 +23 enhancer (49) that incorporated the heart-marking cmlc2:GFP (CG2) transgenesis marker (53), herein referred to as Tg(Runx1:cebpb-CG2) (fig. The gene discussed is RUNX1; the disease is infection.