G6PD and hyperinsulinemic hypoglycemia, familial, 4: This interesting finding suggests that G6PD deficiency itself may contribute to radical curative efficacy, consistent with the protective effect against P. vivax malaria observed in patients with severe G6PDd [28,29] and the observation that the vivax parasitaemia in G6PD Mahidol is lower in G6PD patients compared to G6PD normal patients [30].