To validate the alterations in the quiescent/basal/differentiation axis, we performed multispectral fluorescence staining on esophageal mucosal sections from HC and EoE using established markers of basal (KRT14, p63), suprabasal (IVL), and superficial (CNFN) cell identity (Figure 6A). This evidence concerns the gene TP63 and eosinophilic esophagitis.