A higher percentage of EEC expressed overlapping SOX2, KLF5, and module 7 signature scoring in EoE, with the highest level of coexpression within the same range of pseudotemporal values (Figure 8D and Supplemental Figure 7E), suggesting the regulation of module 7 genes by SOX2 and KLF5. This evidence concerns the gene KLF5 and eosinophilic esophagitis.