Lymphoid neoplasms with dual MYC and BCL6 rearrangements are now considered a subtype of DLBCLNOS, or HGBCL, and their gene expression profiles are highly heterogeneous and unrelated to those of DLBCL/HGB-cell lymphomas with MYC and BCL2 rearrangements. Here, MYC is linked to diffuse large B-cell lymphoma.