As a result, the 5-year survival rate for NF1-associated MPNST, as in the present case, is poor, at 16–30% [3, 4, 17], with a median time to recurrence of 6–9 months and a median time to distant metastasis of 8–9 months [13, 18]. This evidence concerns the gene NF1 and malignant peripheral nerve sheath tumor.