PDX1 and neoplasm: The KPC-Luc-4580 cell line (also known as KPC-4580P) was derived from a tumor that developed in an LSL-KrasG12D/+; LSL-Trp53R172H/+; PDX-1-Cre/+, LSL-ROSA26Luc/+ mouse (35) (Fig. 1A).