Notwithstanding the limitations of the cell‐based studies presented here, we and others have previously indicated that Cav3 loss associated with expression of the LGMD‐1C Cav3P104L mutation results in poor fusion and differentiation of myoblasts and retention of an immature cell signature that may contribute to the myopathic changes in muscle fibre size and necrosis seen in LGMD‐1C patients.7, 39. The gene discussed is CAV3; the disease is rippling muscle disease 2.