FAAH and Anxiety: First, as previously mentioned in the SUD section, FAAH inhibition has been examined in the context of CUD and while the primary outcomes of that study related to the recurrence of cannabis use, it is important to note that elevations in anxiety seen following the cessation of cannabis were found to be significantly attenuated by treatment with the PF-04457845 FAAH inhibitor (D'Souza et al., 2019).