ICAM1 in association with macrophage 1 antigen (MAC-1), CD11b/CD18, lymphocyte function-associated antigen (LFA)-1, CD11a/CD18, and CD11b/CD18 promotes tumor metastasis by activating the immune system and enhancing cell signaling and inflammatory responses (7, 8). The gene discussed is ICAM1; the disease is neoplasm.