(41) used CITE-seq and TCR-seq to analyze tumor-infiltrating lymphocytes (TILs) in NSCLC, and defined a new antigen-reactive T cell molecular tag in terms of the expression of CD39 protein and CXCL13 mRNA to efficiently identify CD4+and CD8+T cells with new antigen-reactive TCRs. The gene discussed is CD8A; the disease is non-small cell lung carcinoma.