To select the most discriminating genes dysregulated in sepsis development, we used LASSO analysis to obtain nine key genes (CHPT1, CPEB4, DNAJC3, MAFG, NARF, SNX3, S100A9, S100A12, METTL9) from the U42 cluster (Figure 5C). This evidence concerns the gene CHPT1 and Sepsis.